Table of Contents
What ingredients are in ondansetron?
Each 5 mL of ZOFRAN oral solution contains 5 mg of ondansetron hydrochloride dihydrate equivalent to 4 mg of ondansetron. ZOFRAN oral solution contains the inactive ingredients citric acid anhydrous, purified water, sodium benzoate, sodium citrate, sorbitol, and strawberry flavor.
Is ondansetron a narcotic?
Is Zofran (ondansetron) a narcotic? No, Zofran (ondansetron) is not a narcotic, instead it belongs to a class of medication called 5-HT3 (serotonin) receptor antagonist.
What class of drug is ondansetron?
Can I take ondansetron and codeine?
Using codeine together with ondansetron can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision.
Is ondansetron a dopamine antagonist?
Pharmacodynamics. Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist, with low affinity for dopamine receptors. The 5-HT3 receptors are present both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone of the area postrema in the medulla.
Is ondansetron abused?
Drug Abuse And Dependence Animal studies have shown that ondansetron is not discriminated as a benzodiazepine nor does it substitute for benzodiazepines in direct addiction studies. Professional side effects, drug interactions, and addiction sections courtesy of the U.S. Food and Drug Administration.
Can ondansetron be used for pain?
This suggests that ondansetron can have an analgesic effect in neuropathic pain. Side effects were minor and infrequent. Implications: The selective 5HT3 receptor antagonist ondansetron, currently used as an antiemetic, may also have analgesic properties.
Can you take Panadol with ondansetron?
No interactions were found between Black and Gold Paracetamol and Zofran. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Why does ondansetron cause serotonin?
These drugs block serotonin, a chemical in the brain that passes signals between nerves. By blocking serotonin, ondansetron shuts down the “chemoreceptor trigger zone,” the area of the brain responsible for the nausea reflex. Zofran is a widely-used drug, but it may not be right for everyone.
Is ondansetron a serotonin antagonist?
Ondansetron is a serotonin receptor antagonist that is effective in preventing and treating PONV.