What is the role of acetylcholinesterase in stimulation of a muscle fiber?

What is the role of acetylcholinesterase in stimulation of a muscle fiber?

Describe the role of acetylcholinesterase in stimulation of a muscle fiber. It is the enzyme that breaks down acetylcholine in the synaptic cleft, ending stimulation of the muscle fiber.

Does acetylcholine stop muscle contraction?

A five-subunit acetylcholine channel coordinates muscle contraction and relaxation by regulating motor neuron excitability in C.

How muscle cells will respond to a lack of acetylcholine?

Muscle cells will become paralyzed when there is a lack of acetylcholine. Clostridium botulinum is a bacterium that produces botulinum toxin that inhibits the release of acetylcholine. The major cause of malignant hyperthermia is uncontrolled release of calcium into the sarcoplasm of muscle cells.

What is Calciums function during muscle contraction?

Calcium binds to the troponin, causing a position change in tropomyosin, exposing the actin sites that myosin will attach to for a muscle contraction (5,6). Without calcium blood would not clot.

What would happen to a skeletal muscle if acetylcholinesterase is inactivated?

Acetylcholinesterase breaks down ACh into fragments that can no longer stimulate the muscle. A single motor neuron and all of the muscle cells that this neuron branches out to synapse with.

What role do acetylcholine and acetylcholinesterase play in muscle contractions?

When a motor nerve cell gets the proper signal from the nervous system, it releases acetylcholine into its synapses with muscle cells. There, acetylcholine opens receptors on the muscle cells, triggering the process of contraction. The cleanup of old acetylcholine is the job of acetylcholinesterase.

How do muscles respond to acetylcholine?

When acetylcholine reaches receptors on the membranes of muscle fibers, membrane channels open and the process that contracts a relaxed muscle fibers begins: Open channels allow an influx of sodium ions into the cytoplasm of the muscle fiber.

What is the role of acetylcholine in muscle cell contraction?

The main job of the neurotransmitter acetylcholine is to carry the signal from nerve cells to muscle cells. There, acetylcholine opens receptors on the muscle cells, triggering the process of contraction.

How does sodium help in muscle contraction?

Sodium stimulates the dephosphorylation of ATP and ADP in the presence of magnesium. This would result in muscle contraction. Others have proposed that the entry of calcium during membrane depolarization initiates contraction of the muscle fibers. Microinjection of minute amounts of calcium produces contraction.

How would a drug that blocks acetylcholine release affect muscle contraction?

How would a drug that blocks acetylcholine release affect muscle contraction? Acetylcholine release is necessary for skeletal muscle contraction because it serves as the first step in the process. A drug that blocks acetylcholine release would prevent binding of ACh with ACh-receptor. Muscle contraction will not occur.